Issue: Issue 13 • Author/s: Annibale Biggeri, Andrea Saltelli
Topics: Epidemiology, Epistemology, Philosophy of Medicine, Philosophy of science
Never as with the present pandemics, numbers and the attendant activities of measuring and modelling have taken centre-stage. Yet these numbers, often delivered by academicians and media alike with extraordinary precision, rely on a rich repertoire of assumptions, including forms of bias, that can significantly skew both the numbers per se and the trust we repose in them. We discuss the issue in relation to a particular case relative to the numbers on excess mortality during the first wave of the Covid-19 pandemic in Italy. We conclude with some considerations…
Issue: Issue 13 • Author/s: Paolo Vineis, Andrea Saltelli
Topics: Epidemiology, Epistemology, Moral Philosophy, Philosophy of Medicine, Philosophy of science
This paper is inspired by a thesis on “immune capital” by Kathryn Olivarius. We suggest that the biological capital, which immunity capital is part of, should be considered as an additional component of the life-course experience of individuals, together with the traditional Bourdieu’s social, economic and cultural capitals that drive their lives. Building upon this concept, we consider the relationships between science, society and policy-making in the course of the pandemic. We suggest that we need to ‘reframe problems so that their ethical dimensions are brought to light’ (Jasanoff), with…
Issue: Issue 13 • Author/s: Virginia Ghiara
Topics: Epidemiology, Epistemology, Philosophy of Medicine, Philosophy of science
In this paper, I argue that evidence of biological and socio-behavioural mechanisms can contribute to the management of Covid-19. I discuss two examples that show how scientists are using different forms of evidence, among which mechanistic evidence, to answer questions about the efficacy of vaccines against Covid-19 and the effectiveness of vaccination interventions in different contexts. In the first example I claim that, due to the fast pace of the pandemic, mechanistic reasoning and evidence of biological mechanisms play an important role in the study of vaccines’ efficacy and the…
Issue: Issue 13 • Author/s: Elena Rocca, Birgitta Grundmark
Topics: Epidemiology, Epistemology, Moral Philosophy, Philosophy of Medicine, Philosophy of science
In this paper, we analyse some of the challenges that pharmacovigilance, the science of detecting and assessing possible adverse reactions from medical interventions, is facing during the COVID-19 pandemic. In particular, we consider the issue of increased uncertainty of the evidence and the issue of dealing with an unprecedented amount of data. After presenting the technical advances implemented in response to these two challenges, we offer some conceptual reflections around such practical changes. We argue that the COVID-19 emergency represents a chance to push forward critical thinking in the field…
Issue: Issue 16 • Author/s: Mauro Dorato
Topics: Epistemology, Metaphysics, Ontology, Philosophy of science, Theoretical philosophy
In the first part of the paper, I discuss three possible ways to achieve some unity between Sellars’ manifest and scientific image of the world. The plurality of scientific methods that I am advocating is compatible with the fact that all empirical sciences strive for beliefs based on the normative concepts of evidence, explanatory power, and experimental accuracy. Such methods provide different means to reach the common purpose of justification. In the second part of the paper, I criticize Sellars’ definition of the manifest image in terms of a suddenly…
Issue: Issue 16 • Author/s: Vincenzo Fano
Topics: Epistemology, Metaphysics, Ontology, Philosophy of science, Theoretical philosophy
Doing metaphysics by building on empirical sciences is a very controversial matter. This paper outlines a middle road between the Scylla of denying the possibility of metaphysics and the Charybdis of doing metaphysics a priori. This is possible if, on the one hand, we accept a moderate form of scientific realism. On the other, we establish a logico-epistemological framework adequate to face the underdetermination of metaphysical theses with respect to our best scientific theories. The case of the debate between eternalism and presentism tests my perspective. In this case study,…
Issue: Issue 13 • Author/s: Carlo Martini
Topics: Epidemiology, Epistemology, Philosophy of Medicine, Philosophy of science
Modelling is a precious source of information in science. With models, we can simplify an otherwise messy reality in order to understand the fundamental driving forces of a system, like an epidemic, and we can try to predict the course of events in complex scenarios where there is a great degree of uncertainty. In short, models can be used to explain and predict phenomena. Yet models interact with expert opinions in two fundamental ways. They are sometimes in competition with expert opinion, and they are sometimes heavily dependent, for their…
Issue: Issue 13 • Author/s: Cecilia Nardini, Fridolin Gross
Topics: Epidemiology, Epistemology, Moral Philosophy, Philosophy of Medicine, Philosophy of science
One of the many peculiar phenomena that the Covid-19 pandemic has brought about is the engagement of non-scientists with specific questions surrounding the interpretation of epidemiological data and models. Many of them have even begun to get involved in the collection, analysis, and presentation of the data themselves. A reason for this might be that the insights that science can provide in a situation of crisis are often inconclusive or preliminary, motivating many people to look for the answers to pressing questions themselves. Moreover, public engagement is facilitated by the…
Issue: Issue 13 • Author/s: Nicolò Gaj, Giuseppe Lo Dico
Topics: Epidemiology, Epistemology, Philosophy of Medicine, Philosophy of science
Unsurprisingly, science has been conferred growing expectations in the context of the COVID-19 pandemic. Accordingly, the issue of dissemination and popularization of scientific outcomes has come to the fore. The article describes the main features of the so-called dominant view in popular science, which is claimed to be implicitly connected to scientism, a stance identifying science as the most (if not the only) reliable source of legitimate knowledge. Scientism’s implicit philosophical roots are argued to lie in naturalism and a trivialized neopositivist concept of science, which underscores the supposed unity…